Alpha-2 Antiplasmin Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2019
Posted by : ptk
on 04:31
Alpha-2 antiplasmin or plasmin inhibitor, is a type of
glycoprotein synthesized by the liver, kidneys and other tissues of the body.
It is a serine protease inhibitor which belongs to the Serpin superfamily that
acts as the primary inhibitor of the serine protease plasmin. Fibrinolysis
occurs due to the conversion of plasminogen to serine protease plasmin by
plasminogen activator. Deficiency of Alpha 2 antiplasmin causes a bleeding
disorder owing to the increase fibrinolysis. Alpha-2 antiplasmin is the protein
responsible for the degradation of fibrin clots and inhibition of
fibrinolysis. Congenital deficiency of this glycoprotein leads to internal
hemorrhage. Alpha-2 antiplasmin is present in two distinct forms which are as
follows:
·
Plasminogen binding
·
Non-plasminogen
binding
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Alpha 2 antiplasmin is used in various diagnostic technologies
such as:
·
Enzyme Linked
Immuno-Sorbent Assay (ELISA)
·
Immunohistochemistry
– Frozen (IHC-F)
·
Immunohistochemistry
– Paraffin (IHC-P)
·
Flow Cytometry
End-users of alpha-2 antiplasmin protein are as follows:
·
Hospitals
·
Clinics
·
Diagnostic labs
·
Private Labs
The aforementioned end users use this protein in patients with
alpha 2 antiplasmin or plasmin inhibitor deficiency especially in patients who
have reported to have significant episodes of internal bleeding following a
minor trauma and bleeding into the joints.Patients with alpha 2 antiplasmin
deficiency often experiences severe medical complications such as:
Prolonged bleeding from wounds
Increased bleeding after consumption of NSAIDs.
Bleeding into joints followed by trauma
Increased muscle bleeding, hematomas and bruising
Bleeding of gastrointestinal tract
Mucosal and CNS bleeding
In the geographical perspective, North America is the leading
market owing to the rise in cases of metabolic syndrome. It has been proved
that excess levels of alpha-2 antiplasmin is associated with metabolic
syndrome and other cardiovascular diseases. Deficiency of alpha-2 antiplasmin
protein causes development of atherosclerotic plaque which results in various
heart diseases.According to the American Heart Association almost 35% of
adults in the U.S. are suffering from metabolic syndrome. Furthermore, the Europe
and Asia-Pacific regions are expected to witness increased market traction due
to increased incidence rate of cardiovascular diseases.
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The major factors driving this market are advances in the
coagulation testing practices, increasing use of automated instrumentation are
rise in cases of cardiovascular diseases. Moreover, factors such as
technological advancement in the hospital infrastructures and high adoption
rate of preventive diagnostic tests are also expected to drive the market.
However, high development costs, need of highly sophisticated instruments and
stringent regulatory policies are some of the restraints that could impede the
growth of the market globally.
Some of the notable players in this industry segment includes
Abbott Laboratories, Axis-Shield plc., Bio/Data Corporation, Becton Dickinson,
Corgenix Medical Corporation, Helena Laboratories, Instrumentation Laboratory,
Roche, Sysmex Corporation and Thermo Fisher Scientific, amongst others.
This research report analyzes this market depending on its
market segments, major geographies, and current market trends. Geographies
analyzed under this research report include
·
North America
·
Asia Pacific
·
Europe
·
Rest of the World
This report provides comprehensive analysis of
·
Market growth
drivers
·
Factors limiting
market growth
·
Current market
trends
·
Market structure
·
Market projections
for upcoming years
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This report is a complete study of current trends in the
market, industry growth drivers, and restraints. It provides market
projections for the coming years. It includes analysis of recent developments
in technology, Porter’s five force model analysis and detailed profiles of top
industry players. The report also includes a review of micro and macro factors
essential for the existing market players and new entrants along with detailed
value chain analysis.
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·
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·
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